2010م - 1444هـ
نبذه عن الكتاب:



Introduction

John Swansbury

1. The Clinical Value of Cytogenetic Studies

in Malignancy

The vast majority of published cytogenetic studies of malignancy

have been of leukemias and related hematologic disorders (see Fig. 1),

even though these constitute only about 20% of all cancers. It follows that most of what is known about the clinical applications of

cytogenetic studies has been derived from hematologic malignancies. More recently, however, there has been a huge expansion in

knowledge of the recurrent abnormalities in some solid tumors, and

it is clear that in these, just as in the leukemias, cytogenetic abnormalities can help to define the diagnosis and to indicate clear prognostic differences. Consequently, cytogenetic studies of some solid

tumors are now also moving out of the research environment and

into routine clinical service.