2008م - 1444هـ
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Abstract This book provides a state-of-the-art description of research in bioinformatics and systems biology as supported by European Commission collaborative

research projects and functions as a practical guide to project websites, participants,

coordinators, publications and key sources. In addition to an introduction to the science, a number of links to key websites and information resources are presented.

This introductory chapter illustrates that bioinformatics and systems biology consist

of more than databases and tools, and are scientific areas in themselves and major

components of most research projects. The key domains for analysis and research

are described in detail. Aspects of collaborative research projects are explored, and

it is shown how they constitute an important research paradigm.

Introduction

Bioinformatics research involves more than the alignment of DNA sequences,

and systems biology involves more than a pathway diagram of the Krebs cycle/

citric acid cycle (Krebs 1953). Bioinformatics databases and analysis tools are

indispensable parts of most life sciences research projects. Increasing numbers of

projects take a “ systematic ” or a systems biology approach. This chapter outlines

the scope and breadth of these related and overlapping fields, which include computational biology and much more besides. It describes how the European

Commission has strengthened these areas and expanded them in new directions

empowered by the paradigm of large-scale collaborative research. Finally, it indicates how this book can be used as a textbook for finding and using the tools and

resources developed, and as a route map to the state of the art of modern biology

and health research.