2010م - 1444هـ
نبذه عن الكتاب:



The information generated by progressive biomedical research is increasing

rapidly, resulting in a tremendous increase in the biological data resource, including protein and gene databases, model organism databases, annotation databases,

biomolecular interaction databases, microarray data, scientific literature data,

and much more. The challenge is in representation, integration, analysis and

interpretation of the available knowledge and data. The book, Knowledge-Based

Bioinformatics: From Analysis to Interpretation, is an endeavor to address the

above challenges. The driving force is the need for more background information

and broader coverage of recent developments in the field of knowledge-based

systems and data-analysis approaches, and their applications to deal with issues

that arise from the current increase of biological data in genomic and proteomic

research. Also, opportunity exists in utilizing these vast amounts of valuable

information for benefit in fitness and disease conditions.

Knowledge-Based Bioinformatics: From Analysis to Interpretation, introduces

knowledge-driven approaches, methods, and implementation techniques for

bioinformatics. The book includes coverage from data-driven Bayesian networks

to ontology-based analysis with applications in the field of bioinformatics. It is

divided into four sections. The first section provides an overview of knowledgedriven approaches. Chapter 1, Knowledge-based bioinformatics, presents the

current status of biomedical research and significance of knowledge-driven

approaches in analyzing the data generated. The focus is on current utilization of

the approaches and further enhancement required for advancing the biomedical

knowledge. Chapter 2, Knowledge-driven approaches to genome-scale analysis,

further explains the concept and covers various systems used for supporting

biomedical discovery in genome-scale data. It emphasizes the importance of

the knowledge-driven approaches for utilizing the existing knowledge