2008م - 1444هـ
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I

was requested by the former controller of examinations at the

University of Madras, India, A. Sivamurthy, to prepare the

curriculum and syllabus for a B.Tech. degree in bioinformatics

at the Vellore Institute of Technology, Vellore, India, in 2001. I was

requested by letter to prepare a project report on a course program

for an M.Tech. degree in bioinformatics by Dr. B. Srinivasan, Vice Chancellor at Sri. Chandrasekharendra Saraswati Viswa Mahavidyalaya

University, Kancheepuram, India, in 2002. The Vice Chancellor at

SASTRA University, Thanjavur, India, R. Sethuraman, chartered me

with the task of writing a book entitled Lecture Notes in Computational

Molecular Biology, to be used for instruction in the newly formed

M.Tech. and B.Tech. bioinformatics programs in 2003.

Since I wrote Lecture Notes in Computational Molecular Biology, a

number of interesting developments in the field of bioinformatics

has come about. The Human Genome Project has been completed

ahead of time. The biologic databases double in size every 10 months,

and the computing speed of microprocessors doubles in speed every

18 months. So a database search that cost $2 today would, two years

from now, quadruple in cost to $8 on account of the explosive growth

of databases and would be cut back in half to $4 on account of the

increase in computing power. There is scope for the development

of data search and data storage algorithms and methods. It can

be viewed as a marriage between information technology and

computational biology. Bioinformatics is emerging as a distinct

discipline of its own. Textbooks need to be neither mathematically

intimidating nor biologically intensive and laborious. Over 560

end-of-chapter exercises are provided in this book. Appendices

with Internet hotlinks to public-domain databases and PERL code

commands are given. This book can be used as a textbook for core

subjects in a bioinformatics undergraduate program and as an elective

for chemical engineering and biotechnology undergraduate and

graduate programs.